Manuel Antonio/Quepos is approximately a 3-hour drive from Costa Rica’s SJO Airport (near San Jose) and an approximately 4-hour drive from the LIR Airport (near Liberia). Upon arrival (and departing), you have several options to get you to the Moonshine Inn and the Manuel Antonio area or back to the airport:
Navigating the winding bends along Route 618 and its offshoot roads is a part of life in Manuel Antonio. Overall, the getting around is quite manageable for most people -- just be careful and take it slow if driving. And it's important to be aware, both as a pedestrian and as driver, that Manuel Antonio (and Costa Rica in general) is not known for its sidewalks, road signs, guard rails or mandatory driving schools. Cars, trucks and motorcycles speed around corners despite the many pedestrians, joggers, bikers and wildlife on the roads. For this reason, we believe it is best to limit the time you're walking along the busier roads. Better options are to drive, taxi/Uber, or take a bus to make your safest way around Manuel Antonio.
Public buses are the choice of locals -- and if you're not opposed to taking the bus, it's by far the most economical option ... bus rides are cheap in Costa Rica. (Examples: SJO Airport to Moonshine Inn: $14 (one way) and a ride from Moonshine to the National Park: About $0.50 (one way). The main bus station in the area is in downtown Quepos (on Avenida Central between Calle Central and Calle 2). Buses arrive and depart from the station to/from several destinations in Costa Rica, most notably San Jose, Puntarenas, Dominical, and Uvita. Buses can also be caught along Route 618 as they travel between Quepos and Playa Espadilla Sur (main public beach in Manuel Antonio). There is a bus stop (and taxi stand) about a 12-minute walk from the front gate of the Moonshine Inn on Route 618.
Manuel Antonio doesn’t have public parking lots so parking can be difficult during the busier tourist times. Moonshine Inn offers its guests free parking as does the Super Joseth grocery story in the center of town (off Route 618) and the two main banks in town with ATMs. There is ample paid parking at the main beach entrance that shouldn't cost more than $10 for the day. Street parking is more available in Quepos.
Official red taxis can be hailed around Manuel Antonio if not hired from where they park off the Lirio Road by the Moonshine Inn. Moonshine Inn also has private taxis/drivers we are happy to arrange for you upon request.
If you decide to rent a car for maximum flexibility and convenience during your trip in Costa Rica (and many people do), we highly advise that you try to avoid driving after dark (which is 6 pm everywhere, everyday). The roads in Costa Rica are much improved in recent years, but there are many, many dangerous driving situations that are common experiences on any day of the week. From heavy rains to unlit stretches of road to pedestrians walking even late at night on the sides of roads to potholes, drunk drivers and poor signage and aggressive drivers, and a million ways to get a flat tire, the risks of driving without the benefit of daylight are, in our opinion, too great to risk. Get your rest at night, get up at the early break of day, and do your driving with the gift of the light of day.